Mara B. Antonoff, MD, FACS, of the University of Texas MD Anderson Cancer Center, joined Lung Cancers Today to discuss what could be on the horizon for surgery in stage IV lung cancer during the 61st Annual Meeting of the Society of Thoracic Surgeons (STS) in Los Angeles.
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The CardioNerds and Dr. Robert Mentz discuss the important steps in treating HF with mineralocorticoid antagonists.
A study compared the risks of cardiovascular events in hospital settings among patients with CKD with and hyperkalemia.
Eli Lilly ended a phase II trial of volenrelaxin in chronic kidney disease "due to a lack of foreseeable clinical benefit."
In the phase II TRANSCEND FL trial the CAR T-cell therapy has shown good efficacy and manageable safety in MZL and FL.
Travere will submit an application to the FDA requesting approval of sparsentan for focal segmental glomerulosclerosis.
Previous studies suggest a link between CKD and sleep disorders, but the nature of the association is unclear.
A review and meta-analysis assessed the influence of SGLT2i therapy on clinically relevant hyperuricemic events.
An increase in intestinal permeability allows gut bacteria to reach bone marrow.
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Dr. Cytryn summarizes a trial in progress investigating a novel immunotherapy combination for gastroesophageal adenocarcinoma
Drs. Finn and Yopp discuss the challenges of defining high-risk patient populations in adjuvant therapy trials for HCC.
Nivolumab plus ipilimumab provided a higher OS and ORR rate, supporting the combination as a potential standard of care.
The combination was shown to provide a 71% response rate, pointing to a new potential treatment for this patient population.
With an OS rate of about 80%, encorafenib and cetuximab with FOLFOX may serve as a new FDA-approved frontline regimen.
Patients with locally advanced GC who achieved pCR after NAC had significantly better survival outcomes.
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In the phase II TRANSCEND FL trial the CAR T-cell therapy has shown good efficacy and manageable safety in MZL and FL.
The menin inhibitor oral agent achieved the KOMET-001 trial's primary endpoints and had a favorable benefit-risk profile.
An expert panel's review finds SCT has often been misattributed as the direct cause of mortality in patients who have SCT.
A study cohort with severe disease over a median follow-up of 14 months had an annualized bleeding rate of zero.
Use is also being explored for T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and mantle cell lymphoma.
Clinicians can use this test to help distinguish more than 60 disease subtypes from patients' normal immune response.