Venous Thromboembolism
The Clinical Practice Guidance document issued by the EHA, ISTH, EAHAD, and ESO addresses both hemophilia A and B.
The reduced-dose oral regimen also had lower incidence of clinically relevant bleeding complications and mortality rate.
In findings arterial thrombosis carried worse overall survival than venous thrombosis in this patient population.
Anthony Sochet, MD, MS, on Knowledge Gaps Affecting Pediatric Inpatient Thromboprophylaxis Decisions
Clinical data is limited in areas such as how to evaluate bleeding risk and when to apply mechanical thromboprophylaxis.
Aspirin was found to be safe and effective in patients with a wide range of VTE risk who underwent total knee arthroplasty.
Efficacy appeared to be similar among DOACs for managing cancer-related VTE, though apixaban may have more favorable safety.
Patients with RA had a 57% increased risk of VTE; a 58% increased risk of DVT; and a 57% increased risk of PE.
Tranexamic acid did not seem to increase risk of postoperative complications in patients undergoing total joint arthroplasty.
Patients treated for isolated superficial vein thrombosis with anticoagulants still had a "substantial" risk of VTE later on.
MPN-associated vascular thromboembolisms were more common in JAK2-mutated diseases and less common in CALR-mutated diseases.
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