The FDA approved trastuzumab deruxtecan for HR-positive/HER2-low metastatic breast cancer based on DESTINY-Breast06 results. The FDA granted Fast Track status to emiltatug ledadotin for advanced breast cancer following phase 1 results targeting B7-H4 Researchers aimed to evaluate the roll of ERCC1 expression in predicting response to adjuvant chemotherapy for TNBC. TILs can serve as a biomarker to identify patients with ERBB2-positive early breast cancer who can reduce adjuvant therapy. Cancer recurrence fear appreciably impacts breast cancer survivors’ ability to re-enter the workforce. There was a 29% increase in cancer detection with AI-supported screening. Researchers found two effective treatments for metaplastic breast cancer. New research has uncovered a combination therapy that shows promising results in melanoma and breast cancer models. Aliya Omer, AstraZeneca, talks about data that backs the efficacy of olaparib in treating high-risk early breast cancer. In patients with high-risk HER2-psoitive breast cancer, adjuvant trastuzumab emtansine reduces the long-term risk of death. The study used SEER data of nearly 20,000 cases. A groundbreaking study has demonstrated that artificial intelligence can enhance breast cancer detection rates by almost 20%. New research on active monitoring versus surgery in DCIS was presented at SABCS 2024. People diagnosed with metastatic breast cancer have a notably increased risk of developing heart disease. Dr. Sadie Dobrozsi discusses the importance of "pan-cancer" testing, especially as it pertains to breast cancer. The CDK4/6 inhibitor showed meaningful improvement in HR+, HER+ disease. The positive predictive value for cancer was 15% higher for those enrolled. The most frequent changes detected were additional copies of chromosome 1q and losses of chromosomes 10q, 16q, and 22. Twelve chemicals were associated with increased breast cancer risk. Heterozygosity in BRCA1 genes is not enough to prevent tumor proliferation, according to researchers out of Harvard.