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This approval for patients aged 12 years and older was based on findings from the explorer7 phase III clinical trial.
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An MDS HSPC signature generated from the model presents possible targets for treatment in patients with low-risk disease.
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The study's results especially highlight potential aberrant gene regulation by ZMAT2 and SMARCD3.
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This approval for patients aged 12 years and older was based on findings from the explorer7 phase III clinical trial.
An MDS HSPC signature generated from the model presents possible targets for treatment in patients with low-risk disease.
The study's results especially highlight potential aberrant gene regulation by ZMAT2 and SMARCD3.
The study showed a mortality risk reduction benefit in certain mutations while for others larger studies are needed.
Researchers noted that confirmation of this relationship in lower-risk disease would require a larger study.
The approval was based on the findings from the phase III MSB-GVHD001 clinical study.
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