Parkinson's disease and melanoma are believed to be linked due to DNA double-strand break repair thus cell proliferation. The primary safety endpoint of minimal SAEs was met as well as the secondary endpoint of increased fluorodopa in the putamen. Dr. Anne Marie Morse discusses the troubling connection between sleep disorders and dementia. The caps on the end of chromosomes are called telomeres. A new model called the Florey Dementia Index (FDI) can accurately predict the age at onset of MCI and AD. The research group will design a vaccine that won't promote inflammation. The phase 2 randomized trial included patients with amyloid-confirmed mild cognitive impairment or early Alzheimer disease. Researchers assessed the molecular underpinnings that may increase the risk of Alzheimer’s disease following TBI. Researchers have developed a novel therapy that selectively removes aggregated tau proteins, which are associated with AD. Dr. Alva discusses a study that evaluated the safety of pimavanserin in frail elderly patients with NDD. Hormone therapy was associated with a 19% lower relative risk in Black women aged 65 to 74 years. Among patients with T2DM, the risk of dementia and Alzheimer disease is lower in those treated with metformin. A 5-minute assessment was found to improve the diagnosis of mild cognitive impairment and dementia. People who inherit a history of Alzheimer disease from their mother's side have a higher risk of developing AD. Midpoint of sleep is associated with multiple measures of sleep quality and could be a biomarker for AD risk. Xanomeline-trospium chloride is effective and well tolerated in patients with schizophrenia experiencing acute psychosis. Individuals who suffer a stroke have a significantly increased risk of developing dementia. Former professional American football players who have medical and mental health conditions are at higher risk of CTE. A novel blood test could be used to effectively screen for Alzheimer disease, even before the onset of symptoms. Rafael Carbunaru talks about a recently approved software that benefits patients with Parkinson disease or essential tremor.