The CardioNerds and colleagues review the differential diagnosis for peripartum cardiomyopathy. A study shows how how advancements in diagnostic tools and treatments for ATTR-CM have improved risk profiles. A recent post-hoc analysis of the ATTRibute-CM trial shows the potential for acoramidis in treating ATTR-CM. A study found an overall decline in surgical myectomy with ICD procedures since 2016. Older adults diagnosed with hypertension can alleviate lung function impairments and mechanics with an active lifestyle. A recent study evaluated the association between resting heart rate and incident atrial fibrillation in Black patients. Exposures included missense variants in TRR associated with increasing transthyretin tetramer destabilization. Pulsatility index and transfer function gain were calculated. Researchers explored how immune checkpoint inhibitors interact with immune cells in arterial plaques. A new study shows that progression from low burden atrial fibrillation (AF) is associated with negative outcomes. Individuals with cardiac implantable electronic devices have a higher risk of tricuspid regurgitation. The CardioNerds discuss a case involving a patient who presented with stress cardiomyopathy leading to cardiogenic shock. The U.S. FDA recently approved Attruby (acoramidis) for adults with ATTR-CM to reduce cardiovascular death, hospitalization. The rise in these regions is despite the overall global decline in incidences. A study highlights the significant HCRU and costs associated with ATTR-CM. Promising long-term outcomes from the ongoing OLE of the ATTRibute-CM trial highlight the efficacy of acoramidis. A case study highlights the importance of avoiding anchoring bias in the diagnosis of cardiac amyloidosis. The diagnosis of AL amyloidosis requires a high index of suspicion to render a prompt diagnosis and appropriate treatment. Mortality rates among inpatients with HF who undergo AF catheter ablation are relatively low. BC survivors undergoing CIED placement have a higher risk of periprocedural complications.