A new study validates a HER2-low–focused scoring system to improve diagnostic accuracy in metastatic breast cancer. Study finds HER2-low vs HER2-zero breast cancer similar overall, but HER2-low shows better RFS if node-positive. The FDA approved trastuzumab deruxtecan for HR-positive/HER2-low metastatic breast cancer based on DESTINY-Breast06 results. The FDA granted Fast Track status to emiltatug ledadotin for advanced breast cancer following phase 1 results targeting B7-H4 Researchers aimed to evaluate the roll of ERCC1 expression in predicting response to adjuvant chemotherapy for TNBC. TILs can serve as a biomarker to identify patients with ERBB2-positive early breast cancer who can reduce adjuvant therapy. Cancer recurrence fear appreciably impacts breast cancer survivors’ ability to re-enter the workforce. There was a 29% increase in cancer detection with AI-supported screening. Researchers found two effective treatments for metaplastic breast cancer. New research has uncovered a combination therapy that shows promising results in melanoma and breast cancer models. Aliya Omer, AstraZeneca, talks about data that backs the efficacy of olaparib in treating high-risk early breast cancer. In patients with high-risk HER2-psoitive breast cancer, adjuvant trastuzumab emtansine reduces the long-term risk of death. The study used SEER data of nearly 20,000 cases. A groundbreaking study has demonstrated that artificial intelligence can enhance breast cancer detection rates by almost 20%. New research on active monitoring versus surgery in DCIS was presented at SABCS 2024. People diagnosed with metastatic breast cancer have a notably increased risk of developing heart disease. Dr. Sadie Dobrozsi discusses the importance of "pan-cancer" testing, especially as it pertains to breast cancer. The CDK4/6 inhibitor showed meaningful improvement in HR+, HER+ disease. The positive predictive value for cancer was 15% higher for those enrolled. The most frequent changes detected were additional copies of chromosome 1q and losses of chromosomes 10q, 16q, and 22.