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2021 ASH Annual Meeting & Exposition
Focus on GVHD for Pharmacists
Focus on CAR T-Cell
Focus on CLL, MCL, WM
Focus on MDS
Liso-cel Versus Standard of Care as Second-Line Therapy for Relapsed/Refractory LBCL
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 3, 2023
The chimeric antigen receptor (CAR) T-cell therapy lisocabtagene maraleucel (liso-cel) significantly improved event-free ...
Tisa-Cel Found Noninferior to Standard of Care in Relapsed/Refractory Aggressive B-Cell NHL
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
According to results from the phase III BELINDA trial, patients with relapsed/refractory aggressive B-cell non-Hodgkin ...
ZUMA-7: Benefits of Axi-Cel Persist Over Current Standard of Care in Aggressive B-Cell Lymphoma
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
The chimeric antigen receptor (CAR) T-cell therapy axicabtagene ciloleucel (axi-cel) demonstrated significant and ...
Ibrutinib Plus FCR Could Provide Functional Cure in Young CLL Patients
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
At more than three years of follow-up, most patients with chronic lymphocytic leukemia (CLL) who were treated with a ...
Three-Drug Daratumumab-Based Combination Proves Effective in Real-World Patients
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
According to the presentation at the 2021 American Society of Hematology Annual Meeting, real-world patients with ...
Black Patients Are Severely Under-Represented in Pivotal CAR T-Cell Clinical Trials
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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August 30, 2023
Pivotal trials that supported Food and Drug Administration (FDA) approval of chimeric antigen receptor (CAR) T-cell ...
Polycythemia Vera Patients Have Improved Hematocrit Response With Rusfertide
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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September 26, 2023
Treatment with the investigational injectable hepcidin mimetic rusfertide effectively controlled levels of hematocrit ...
High Complete Response Rates With Magrolimab and Azacitidine Plus Venetoclax in Newly Diagnosed, High-Risk Acute Myeloid Leukemia
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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August 30, 2023
According to results from a phase I/II study, more than 90% of older and high-risk patients with newly diagnosed acute ...
Axicabtagene Ciloleucel Produces High Complete Response Rates in Large B-Cell Lymphoma
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ASH Annual Meeting and Exposition 2021
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April 3, 2023
First-line treatment with the autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy axicabtagene ...
Anti-BCMA CAR T-Cell Therapy CT103A Provides Rapid, Durable Responses
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
In a single-arm phase I/II study, infusion with CT103A, a novel fully human B-cell maturation antigen (BCMA)-targeted ...
CAR T-Cell Therapy Recipients May Have Higher Unplanned Use of Healthcare Resources
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
Chimeric antigen receptor (CAR) T-cell therapy is a potentially life-saving option for patients with hematologic ...
BELINDA: Tisa-Cel Noninferior to Standard of Care in Relapsed/Refractory Aggressive B-Cell NHL
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
According to results from the phase III BELINDA trial, patients with relapsed/refractory aggressive B-cell non-Hodgkin ...
Study Suggests Peripheral Blood Cytopenias Represent an Early Marker of Cancer Mortality Risk
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
According to findings from the REGARDS trial, peripheral blood cytopenias may be associated with a higher risk of ...
Oncology Advanced Practice Providers Face Constraints on Prescribing Authority
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
According to a poster presentation at the 2021 American Society of Hematology, prescribing chemotherapy is not a ...
Comparing Asciminib With Bosutinib in Patients With Chronic-Phase Chronic Myeloid Leukemia
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
According to results from the ASCEMBL trial, asciminib was superior to bosutinib in inducing major molecular responses ...
Final Analysis of the EURO-SKI Study Suggests CML Patients Can Safely Stop TKI Inhibitors
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
For patients with chronic myeloid leukemia (CML), treatment with tyrosine kinase inhibitors (TKIs) has increased the ...
Acalabrutinib Associated With High PFS Benefit in Relapsed/Refractory CLL
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ASH Annual Meeting and Exposition 2021
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April 6, 2023
According to three-year follow-up data from the ASCEND trial, patients with relapsed/refractory chronic lymphocytic ...
Zanubrutinib Plus Venetoclax Well-Tolerated, Effective as First-Line Therapy for CLL/SLL With Del17p
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ASH Annual Meeting and Exposition 2021
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April 6, 2023
Preliminary data from a nonrandomized arm of the SEQUOIA trial, presented at the 2021 Annual Meeting of the American ...
Older Patients With Newly Diagnosed CLL Benefit From Frontline Targeted Treatment
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
Although individuals older than 80 years make up more than 20% of cases of chronic lymphocytic leukemia (CLL), this ...
Evaluating Frontline Ibrutinib Plus Venetoclax in Chronic Lymphocytic Leukemia
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
According to a study presented at the 2021 American Society of Hematology Annual Meeting, frontline treatment with ...
Transplant Proves Beneficial for Patients With Waldenström Macroglobulinemia
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
According to a study that reviewed response and survival outcomes in Waldenström macroglobulinemia (WM) patients who ...
Teclistamab Continues to Produce Durable Responses in MajesTEC-1 Trial
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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August 31, 2023
The bispecific antibody teclistamab displayed a manageable safety profile at the recommended phase II dose and continued ...
Examining the Diversity of Pivotal CAR T-Cell Clinical Trial Enrollment
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
Pivotal trials that supported Food and Drug Administration (FDA) approval of chimeric antigen receptor (CAR) T-cell ...
Zanubrutinib Plus Venetoclax as First-Line Therapy for CLL/SLL With Del17p
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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May 2, 2023
Preliminary data from a nonrandomized arm of the SEQUOIA trial, presented at the 2021 Annual Meeting of the American ...
Study Finds First-Line Targeted Treatment for CLL Is Beneficial in Elderly Patients
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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May 15, 2023
Although individuals older than 80 years make up more than 20% of cases of chronic lymphocytic leukemia (CLL), this ...
Rituximab, Bendamustine, and Bortezomib Combination Improves Responses in Relapsed/Refractory Waldenström Macroglobulinemia
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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May 2, 2023
Second-line therapy comprising standard rituximab plus bendamustine and bortezomib was effective and well-tolerated as a ...
Study Investigates Patient Preferences in Waldenström Macroglobulinemia Treatment
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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May 2, 2023
A mixed-method study of Dutch patients, presented at the 63rd American Society of Hematology Annual Meeting & ...
Frontline Rituximab-Bendamustine Combination Shows Sustained Efficacy in Older MCL Patients
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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May 2, 2023
At the 2021 American Society of Hematology (ASH) Annual Meeting, researchers presented long-term follow-up data from a ...
Assessing Costs and Resource Utilization of Hospital-Based Care Among Patients with B-Cell Malignancies
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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May 2, 2023
Patients with mantle cell lymphoma (MCL), Waldenström macroglobulinemia (WM), marginal zone lymphoma (MZL), and chronic ...
Evaluating Adoptive Immunotherapy to Prevent Acute GVHD
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
Adoptive immunotherapy with CD4+/CD25/+FOXP3+ regulatory T cells (Tregs) and conventional T cells (Tcons) has been used ...
Evaluating Mosunetuzumab and Polatuzumab Vedotin in Relapsed/Refractory B-Cell NHL
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
Mosunetuzumab was safe and efficacious for patients with heavily pretreated relapsed and/or refractory B-cell ...
Study Reviews Response and Survival Outcomes of Transplant for Waldenström Macroglobulinemia
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
A study that reviewed response and survival outcomes in Waldenström macroglobulinemia (WM) patients who underwent ...
GRIFFIN: Long-Term Follow-up Shows Durability of Daratumumab Responses in Transplant-Eligible Myeloma
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
According to extended follow-up from the GRIFFIN trial, the combination of daratumumab and lenalidomide, bortezomib, and ...
Evaluating Ivosidenib in Patients with IDH1-Mutated Myelodysplastic Syndrome
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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August 30, 2023
Results from the phase II IDIOME trial suggest that ivosidenib, a small-molecule mutant IDH1 inhibitor, showed good ...
Adding Gene Mutations to the IPSS Improves Risk Stratification for MDS
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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August 30, 2023
For patients with myelodysplastic syndromes (MDS), an updated International Prognosis Scoring System (IPSS) that ...
Researchers Describe a New Single-Cell Multi-Omic Analysis to Understand TP53-Mediated Evolution of Malignancies
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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August 25, 2023
TP53 is the most commonly mutated gene in human cancer. Presence of “multi-hit” TP53 mutations is associated with ...
Combination of Venetoclax Plus FLAG-IDA Leads to High Response Rates in Newly Diagnosed AML
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 13, 2023
According to research presented during the 2021 ASH Annual Meeting, induction and consolidation therapy comprising ...
Adding Sabatolimab to HMAs Appears to Be a Safe, Effective Option in MDS and AML
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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August 30, 2023
In an open-label, multicenter study presented at the 2021 ASH Annual Meeting, the combination of sabatolimab and ...
Could Improved Access to Transfusion Services Increase Hospice Enrollment?
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 6, 2023
Patients with hematologic malignancies who may require blood transfusions are often unable to enroll in hospice care ...
Magrolimab Plus Azacitidine With Venetoclax Considered “Highly Effective” in Newly Diagnosed, High-Risk Acute Myeloid Leukemia
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 13, 2023
The combination of magrolimab with venetoclax and azacitidine was considered safe and highly effective in older and ...
Study Validates IMWG Frailty Scoring in Relapsed/Refractory Multiple Myeloma
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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May 2, 2023
At the 2021 American Society of Hematology Annual Meeting and Exposition, Fabio Efficace, PhD, and a team of researchers ...
Enrollment of Black Americans in Pivotal Chimeric Antigen Receptor-T Cell Clinical Trials
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 3, 2023
Black Americans were severely under-represented in clinical trials that supported FDA approvals of chimeric antigen ...
Four-Drug Regimen of Dara-KRd Plus AHCT and Consolidation Induces MRD Negativity
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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July 5, 2023
According to findings presented at the 2021 ASH Annual Meeting, the combination of daratumumab, carfilzomib, ...
Updated Results From the MajesTEC-1 Trial of Teclistamab
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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August 31, 2023
Findings from phase II of the phase I/II MajesTEC-1 study on teclistamab were presented for the first time at the 2021 ...
Examining Racial Disparities in Treatment and Outcomes of Waldenström Macroglobulinemia Patients
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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December 13, 2021
In a study conducted presented at the 2021 American Society of Hematology Annual Meeting, researchers led by Aisha S. ...
Promising Results With Magrolimab Added to Azacitidine With Venetoclax in Newly Diagnosed, High-Risk Acute Myeloid Leukemia
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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December 9, 2022
The treatment combination of azacitidine with venetoclax and magrolimab was safe and highly effective in older and ...
CAR T-Cell Therapy Tisa-Cel Noninferior to Standard of Care in Relapsed/Refractory Aggressive B-Cell NHL
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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December 9, 2022
Patients with relapsed/refractory aggressive B-cell non-Hodgkin lymphoma (NHL) who received second-line treatment with ...
Better Access to Transfusion Services Could Improve Hospice Enrollment
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 24, 2023
Patients with hematologic malignancies who may require blood transfusions may not be able to enroll in hospice care ...
Analysis Identifies Factors Prognostic of Ruxolitinib Failure in Chronic GVHD
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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April 24, 2023
Updated results from a real-world analysis confirm that ruxolitinib is an effective treatment option for patients with ...
Pirtobrutinib in Patients with Previously Treated Mantle Cell Lymphoma
DocWire News Editors
ASH Annual Meeting and Exposition 2021
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May 2, 2023
According to updated data from the phase I/II BRUIN study, presented at the 2021 American Society of Hematology Annual ...
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