Ajay Singh pays tribute to the late nephrologist and researcher Nicolaos Madias, MD, of Tufts Medical Center. The four-pillar approach to treating diabetic kidney disease (DKD) has been endorsed by high-quality trials, such as FLOW. IgA nephropathy (IgAN) is on the cusp of a transformational change in its treatment. APRIL has emerged as a critical factor in the pathogenesis of IgAN and is the focus of several clinical development programs. The benefit-risk ratio and considerations about unmet need are worth considering. SGLT2i therapy is contraindicated in patients with type 1 diabetes mellitus (T1DM) who have CKD. The first part of the dialysis moonshot is to prevent the need for dialysis. Measuring eGFR and UACR is a key component of guideline-directed medical therapy for patients with CKD from type 2 diabetes. The most important patients who should receive treatment with SGLT2 inhibitors are those with CKD and type 2 diabetes. Sodium-glucose transport protein 2 (SGLT2) inhibitors (SGLT2i), or gliflozins, block SGLT2 cotransporters in the ... Managing blood pressure is probably the most important intervention that a nephrologist pursues in slowing kidney ... Approximately 221 million people worldwide have been diagnosed with infection from SARS-CoV-2, the virus that causes ... The approval by the US FDA on August 23, 2021, of difelikefalin (marketed as Korsuva™ by Cara Therapeutics) is a major ... In a thought-provoking Viewpoint article in JAMA Surgery1, Arthur Matas, MD, makes the case for introducing a regulated ...