Camizestrant plus CDK4/6 inhibition significantly improved PFS in HR+/HER2– advanced breast cancer with ESR1 mutations. Dr. Timothy Yap discusses the PETRA trial, which showed the efficacy of saruparib in treating HER2-negative breast cancer. The phase II MAINTAIN trial evaluated the efficacy of adding ribociclib to endocrine therapy in patients with hormone ... In the phase II SYSUCC-005 trial, researchers explored the effectiveness of switching treatment modalities after ... The U.S. Food and Drug Administration granted accelerated approval to Enhertu® (fam-trastuzumab deruxtecan-nxki) for ... Trastuzumab deruxtecan demonstrated durable anti-tumor activity in previously treated patients with human epidermal ... The investigational bispecific T-cell engager (BiTE) PRS-343 was well tolerated and demonstrated anti-tumor activity in ... A group of researchers has recently identified several genetic mutations associated with severe breast cancer. This ...