ASH 2023: Focus on Myelofibrosis

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Rob DillardConference Coverage | December 14, 2023
A noninvasive magnetic resonance imaging technique can effectively evaluate bone marrow in patients with myelofibrosis.
Rob DillardConference Coverage | December 14, 2023
CALR-1 mutation is an important risk factor for both drug survival and longevity in momelotinib-treated patients with MF.
Rob DillardConference Coverage | December 18, 2023
A significant proportion of patients with myelofibrosis undergoing HSCT experience poor graft function.
Rob DillardConference Coverage | December 12, 2023
Transfusion independence response was linked to bone marrow reticulin fibrosis improvement in patients with myelofibrosis.
Rob DillardConference Coverage | December 12, 2023
A study found that JAK2 V617F mutations were associated with improved OS and PFS after HCT in patients with myelofibrosis.
Rob DillardConference Coverage | December 12, 2023
The Reticulin, Collagen, Osteosclerosis score is clinically and prognostically relevant in secondary myelofibrosis.
Rob DillardConference Coverage | December 12, 2023
Changes in bone marrow microbiome and proteome can help distinguish between patients with ET and those with prefibrotic PMF.
Rob DillardConference Coverage | December 12, 2023
Patients with relapsed or refractory MF treated with TP-3654 monotherapy showed promising early outcomes.
Rob DillardConference Coverage | December 12, 2023
A study compared health-related QOL and symptom burden in patients with prefibrotic MF and those with overt MF.
Rob DillardConference Coverage | December 12, 2023
More than half of patients with low-risk myelofibrosis have evidence of disease progression.
Rob DillardConference Coverage | December 12, 2023
The risk of CV-related mortality risk in patients with primary MF has not increased following the approval of ruxolitinib.
Rob DillardConference Coverage | December 12, 2023
Megakaryocytes derived PF4 play an important role in the progression of myelofibrosis.
Rob DillardConference Coverage | December 12, 2023
Serial sensitive molecular monitoring of JAK2 at defined points is a viable predictive marker for relapsed myelofibrosis.
Rob DillardConference Coverage | December 12, 2023
In vivo T-cell depletion with antithymocyte/antilymphocyte globulin prior to HSCT is effective at reducing GVHD.
Rob DillardConference Coverage | December 12, 2023
Treating myelofibrosis patients with ruxolitinib before, during, and after HSCT is safe and effective.
Rob DillardConference Coverage | December 12, 2023
Persistence of cells with MF-associated driver mutations following allogeneic HSCT was linked to outcomes.
Rob DillardConference Coverage | December 12, 2023
Ropeginterferon alfa-2b is an effective treatment for patients with primary myelofibrosis in the pre-/early fibrotic stage.
Rob DillardConference Coverage | December 12, 2023
Hemoglobin and platelets are associated with overall survival in patients with myelofibrosis following allogeneic HSCT.
Rob DillardConference Coverage | December 12, 2023
Treatment-naïve myelofibrosis patients who received navitoclax plus ruxolitinib saw a significant reduction in spleen ...
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