Cancer organoid-based drug sensitivity tests have recently been investigated to predict responses to anticancer drugs. A study that assessed the impact of miR-29a and miR-143 on gene expression in lung cancer. A study that examined whether the combination of AI and knowledge can identify more patients with lung and ovarian cancers. Women with cardiovascular disease are treated with cholesterol-lowering therapies less often than men. Climbing stairs is associated with improved heart health and a lower risk of cardiovascular disease. Air pollution is linked to stress and depression, and as a result, it puts middle-aged adults at risk of dying from CVD. A study examined whether AI and clinical knowledge can identify more patients with lung and ovarian cancers. A study detailed the landscape of lung adenocarcinoma progression. MK-1084 as monotherapy and in combination with pembrolizumab is effective in patients with NSCLC. Dr. Townsend details the science behind aldosterone, the hormone that regulates sodium and helps regulate blood pressure. Dr. Townsend discusses hypertension and how not adhering to medications is the biggest issue for patients. Dr. Timothy Yap discusses the PETRA trial, which showed the efficacy of saruparib in treating HER2-negative breast cancer. Darwin Kwok discusses how he felt about winning the award and what he’s learned from past recipients. A blood-based machine learning assay may be able to differentiate patients with ovarian cancer from healthy patients. Physical inactivity was significantly correlated with worse cardiometabolic risk in a large ambulatory patient population. Patients with a history of venous thromboembolism were more likely to receive VTE prophylaxis. Patients ≥70 years of age were more likely to have a reduction in their palbociclib dosage. Rates of treatment-related hypersensitivity reactions were low in an academic community setting. Same-day administration of pegfilgrastim was not linked to a greater incidence of grade ≥3 neutropenia. A machine learning-powered analysis of Google Street View shows how environment impacts risk of major adverse cardiac events.