Targeted discovery proteomics and transcriptomics approaches were used. Dr. Shaun Grannis talks about a large-scale study which showed the robust efficacy of RSV vaccine in older adults. A cross-sectional study aimed to assess RSV rates before the 2023 vaccine introduction. The recent increase in extreme weather events is increasing both waterborne and mosquito-borne infections. The index date marked the start of the respiratory episode that involved hospitalization or a diagnosis of RSV or flu. Researchers compared four RSV seasons, two before and two during the COVID-19 pandemic. Preliminary data highlight the potential of rAAV5 vectors in RSV immunity. Public worry about contracting RSV has appreciably dropped in the past year, though not worry about COVID-19 or seasonal flu. RSV vaccination is effective at preventing hospitalizations and trips to the emergency room in older adults. A plant-based diet may reduce cardiovascular risk in people with HIV. Greater than half of infants insured with Medicaid who were diagnosed with HIV not receive preventative treatment. COVID-19 infection may increase the risk of heart attack, stroke and all-cause mortality up to three years post-infection. There are significant challenges in achieving diabetes control in patients with both diabetes and HIV. A two-dose schedule administered just one week apart can potentially increase the efficacy of an HIV vaccine. A study used a novel combination approach to increase understanding of the negative effect efavirenz has on the brain. Metformin may help deplete the viral reservoir and eliminate it in people living with HIV undergoing antiretroviral therapy. The study will provide HIV prevention, diagnosis, and treatment for incarcerated people with opioid use disorder. An experimental drug originally developed to treat cancer shows potential in clearing HIV from infected cells in the brain. COVID-19 infection accelerates disease progression in children and adolescents with presymptomatic type 1 diabetes. Lisa Barr discusses what's being done to bring us closer to an HIV-free future.