Dr. Shaun Grannis talks about a large-scale study which showed the robust efficacy of RSV vaccine in older adults. A cross-sectional study aimed to assess RSV rates before the 2023 vaccine introduction. The index date marked the start of the respiratory episode that involved hospitalization or a diagnosis of RSV or flu. Researchers compared four RSV seasons, two before and two during the COVID-19 pandemic. Preliminary data highlight the potential of rAAV5 vectors in RSV immunity. Public worry about contracting RSV has appreciably dropped in the past year, though not worry about COVID-19 or seasonal flu. RSV vaccination is effective at preventing hospitalizations and trips to the emergency room in older adults.