Smoking and Incident Rheumatoid Arthritis

By DocWire News Editors - Last Updated: April 7, 2023

Smoking cigarettes have been proven to cause a varying array of health issues, including causing diseases, increasing the risk of cancer, and reducing the health of smokers in general. In a recently published study in Rheumatology, researchers aimed to investigate the link between smoking status, including childhood and adult passive exposure, and the risk of incident rheumatoid arthritis (RA). 

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Researchers used the French E3N cohort, which included 98,995 female volunteers; participants were prospectively followed since 1990. The study authors collected data through questionnaires, sent every 2 to 3 years, and requested information on medical events, general, lifestyle and environmental characteristicsIn 3 successive questionnairesRA diagnoses were collected and confirmed if women received reimbursement for an RA-specific medication 

https://twitter.com/physionico/status/1030144205824434176

Results of the study showed that among 71,248 women, 371 incident RA cases were confirmed. Ever-smokers not exposed to passive smoking had an increased risk of RA [1.38 (95% CI 1.10, 1.74)]Results also showed that ever-smokers who also had childhood passive smoking exposure had a higher risk of RA than smokers not exposed during childhood [HR 1.67 (95% CI 1.17, 2.39)], but without a significant difference (p=0.30). 

“(The study) suggests for the first time that passive exposure to tobacco during childhood might also increase the risk of RA in future light smokers and probably non-smokers,” the researchers concluded. “Our results highlight the importance of avoiding any tobacco environment in children, especially in those with a family history of RA.” 

For more about rheumatoid arthritis, check out an article on rheumatoid arthritis and diabetes screening rates. 

SOURCE: Rheumatology 

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