Dr. Chadi Nabhan is joined by Dr. Manmeet Ahluwalia, deputy director, chief scientific officer, and chief of solid tumor medical oncology at the Miami Cancer Institute, to delve into the latest breakthroughs in primary brain cancers. An esteemed expert in brain metastases and primary brain tumors, Dr. Ahluwalia provides invaluable insight into clinical trial design, enrollment challenges, and the complexities of brain tumor development. Together, Drs. Nabhan and Ahluwalia explore the landscape of surgical and therapeutic interventions in brain cancer, uncovering advancements in survival rates, quality-of-life enhancements, promising therapeutic agents targeting specific mutations, and much more.