HER2-Positive Breast Cancer
Pembrolizumab plus dual HER2 blockade may offer a chemo-free option for early HER2+ breast cancer, phase 2 data suggest. Enhertu plus THP improved pCR over standard chemo in high-risk HER2+ early breast cancer, DESTINY-Breast11 shows.
Dr. Soliman explores dendritic cell vaccines to boost immunity and cut chemo toxicity in early HER2-positive breast cancer. Pilot study shows HER2-targeted dendritic cell vaccines may enhance immune response in early HER2-positive breast cancer. Enhertu plus pertuzumab significantly improved PFS vs. THP in 1L HER2+ mBC, marking the first advance in over a decade. The CDK4/6 inhibitor showed meaningful improvement in HR+, HER+ disease. A year of treatment with the antibody-drug conjugate trastuzumab emtansine effectively prevents HER2-positive BC ... Eribulin is noninferior to trastuzumab and pertuzumab plus taxane in treating HER2-positive breast cancer. The HER2DX ERBB2 mRNA score was significantly associated with improved survival in patients with metastatic HER2+ BC. Using the HER2DX genomic tool is feasible in a real-world setting of patients with early-stage HER2-positive breast cancer. CNS radiotherapy with pyrotinib and capecitabine improves CNS progression in breast cancer patients with brain metastases. Will HER2CLIMB-02 study data impact the breast cancer landscape? In a recent study, published in JAMA Oncology, researchers evaluated whether the HER2DX assay could predict ... Researchers of a study, published in Radiotherapy and Oncology, evaluated the effects of post-mastectomy radiation ...