Allogeneic hematopoietic stem cell transplantation

Absolute Neutrophil Counts Before HSCT Have Prognostic Value in Aplastic Anemia

Andrew MorenoAnemia | July 24, 2024

Before performing allogeneic HSCT in AA patients, clinicians should measure ANC as a prognostic factor.

Glutaminase May Be a Therapeutic Target in Ph- and JAK2-V617F-Driven MPNs

Rob DillardASCO 2023 | August 25, 2023

The up-regulation of glutaminase is a common feature in Philadelphia-negative and JAK2-V617F-driven MPNs.

Adding Itacitinib to Conventional GVHD Prophylaxis

Patrick DalyASH Annual Meeting 2022 | August 28, 2023

In a recent study, researchers from the Hope National Medical Center in Duarte, California, evaluated the safety and ...

GVHD Is Associated with Reduced Antibody Response to COVID-19 Vaccine

Rebecca AraujoCOVID-19 | July 7, 2023

A study published in the Journal of Hematology & Oncology found that chronic graft-versus-host disease (GVHD) is ...

Long-term Risk of Frailty in Survivors of Blood or Bone Marrow Transplantation

Kaitlyn D’OnofrioOncology | July 5, 2023

A study examined longitudinal trends in the frailty state of blood or bone marrow transplantation (BMT) survivors. The ...

Clinically Significant GVHD in Children Associated with Notably Lower Survival

Rob DillardTCT 2021 | August 29, 2023

Clinically significant graft-versus-host disease (CSGVHD) in children is associated with considerably reduced survival, ...

Intestinal Pneumatosis and Perforation Are a Rare but Serious Complication of Gastrointestinal GVHD

Rob DillardTCT 2021 | July 5, 2023

Pneumatosis and/or perforation represents a rare, yet extremely serious complication of acute gastrointestinal (GI) ...

Analysis of GVHD Treatment Abroad

Rob DillardTCT 2021 | July 5, 2023

Less than half of patients in low-to-middle-income countries with severe chronic graft-versus-host disease (cGVHD) who ...

Conditioning Regimen Impacts Outcomes Following Allogeneic Hematopoietic Cell Transplant in Myelofibrosis

Rob DillardTCT 2021 | September 26, 2023

Conditioning regimen intensity has a significant impact on clinical outcomes following allogeneic hematopoietic cell ...

Assessing the Clinical Impact of Post-Transplant Splenectomy in Primary Myelofibrosis

Rob DillardTCT 2021 | September 26, 2023

Researchers reported two cases of post-allogeneic hematopoietic cell transplant (alloHCT) splenectomy and found that ...

Systematic Review Compares Allogeneic Hematopoietic Cell Transplant Versus Gene Therapy in Sickle Cell Disease

Kerri FitzgeraldASH Annual Meeting 2020 | August 29, 2023

Sickle cell disease (SCD) shortens life expectancy and leads to morbidity. Recent advancements in allogeneic ...

Study Shows Significant Improvements Since 1984 in Survival Rates After Allogeneic Transplantation

DocWire News EditorsASH Annual Meeting 2020 | August 30, 2023

A study presented at the 62nd ASH Annual Meeting & Exposition demonstrated that allogeneic hematopoietic cell ...

Bortezomib-Based Induction Before AHCT Is Beneficial For Low Disease Burden AL Amyloidosis

Rebecca AraujoOncology | July 5, 2023

Patients with light-chain (AL) amyloidosis with low disease burden who are eligible for autologous hematopoietic cell ...

Acute Leukemia Treatment Guidelines, Repercussions Amid the COVID-19 Pandemic

Kaitlyn D’OnofrioCOVID-19 | September 21, 2023

An article published in Leukemia Research outlined factors to consider when treating patients with acute leukemia during ...

MIPSS70+ v2.0 Predicts Long-Term Survival in Myelofibrosis After Allogeneic HCT with Flu/Mel Conditioning Regimen

DocWire News EditorsSOHO 2019 | September 26, 2023

Allogeneic hematopoietic cell transplantation (allo-HCT) used in conjunction with fludarabine/melphalan (Flu/Mel) ...

Jonathan U. Peled, MD: Disruptions in the Gut Microbiota on Post-Transplantation Outcomes

Kerri FitzgeraldASH Annual Meeting 2018 | July 7, 2023

Jonathan U. Peled, MD, of Memorial Sloan Kettering Cancer Center discusses his study which looked at whether pre-HCT ...

Fecal Microbiota Transplantation Helps Cancer Patients

Kaitlyn D’OnofrioOncology | June 29, 2023

A new study found that autologous fecal microbiota transplantation (auto-FMT) in cancer patients can help reestablish ...