The phase 2 trial included patients who had advanced or metastatic NSCLC with actionable genomic alterations. The efficacy of ensartinib was evaluated in eXALT3, an open-label, randomized, active-controlled, multicenter trial. Shirish M. Gadgeel, MD, discusses the phase 1/2 ARROS-1 and ALKOVE-1 studies presented at the ESMO 2024 Congress. Ken Culver, MD, Director of Research and Clinical Affairs at ALK Positive, discusses the on-going ALK Life Study.