Christopher Lieu, MD, of University of Colorado Medicine, reviews the CheckMate 9DW trial that was presented at ASCO GI 2025, which examined nivolumab plus ipilimumab against lenvatinib plus sorafenib in patients with advanced or unresectable hepatocellular carcinoma.
Nivolumab plus ipilimumab provided a higher OS and ORR rate, supporting the combination as a potential standard of care for this disease.