In part 2 of the DocWire News interview with Raymond Townsend, MD, FAHA, a professor of medicine and director of the hypertension program at the Hospital of the University of Pennsylvania, Dr. Townsend details the science behind aldosterone, the hormone that regulates sodium and potassium levels and plays a pivotal role in maintaining blood pressure. Aldosterone dysregulation, as Dr. Townsend explains, may contribute to the pathophysiology of hypertension, and it may be associated with an increased risk of adverse cardiac and renal outcomes.