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2020 ASH Annual Meeting & Exposition
Focus on CLL, MCL, and WM
Focus on DLBCL
Focus on MDS
ASH 2020: Highlights in Multiple Myeloma, with Dr. Hari
Rebecca Araujo
ASH Annual Meeting 2020
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April 28, 2023
DocWire News spoke with Parameswaran Hari, MD, Chief of Hematology/Oncology at the Medical College of Wisconsin, about ...
Are Oral Anticoagulants Effective Against VTE in Patients with Multiple Myeloma?
Rebecca Araujo
ASH Annual Meeting 2020
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August 30, 2023
According to data presented at the 2020 American Society of Hematology Annual Meeting & Exposition, the use of ...
Dr. Tony Lin Summarizes Venclexta Data Presented at ASH
Kaitlyn D’Onofrio
ASH Annual Meeting 2020
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August 30, 2023
The all-virtual 62nd ASH Annual Meeting & Exposition highlighted some of the newest data about Venclexta. DocWire ...
Dr. Callaghan Talks About HAVEN Study Investigating Emicizumab in Patients with Hemophilia A
Kaitlyn D’Onofrio
ASH Annual Meeting 2020
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August 25, 2023
During the all-virtual 62nd ASH Annual Meeting & Exposition, Michael U. Callaghan, MD, Associate Professor of ...
Systematic Review Compares Allogeneic Hematopoietic Cell Transplant Versus Gene Therapy in Sickle Cell Disease
Kerri Fitzgerald
ASH Annual Meeting 2020
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August 29, 2023
Sickle cell disease (SCD) shortens life expectancy and leads to morbidity. Recent advancements in allogeneic ...
Zeta Globin Gene Expression May Lead to Therapy for Alpha Thalassemia Major
Kerri Fitzgerald
ASH Annual Meeting 2020
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August 29, 2023
Alpha-globin mutations are common, and the number and type of mutated alleles will determine the severity of subsequent ...
Long-Term Data Support AMT-060 Gene Therapy in Hemophilia B
Kerri Fitzgerald
ASH Annual Meeting 2020
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August 25, 2023
At the all-virtual 62nd ASH Annual Meeting & Exposition, researchers presented data from an ongoing phase I/II trial ...
Researchers Test New CAR-T Technology in Solid Tumors
Kerri Fitzgerald
ASH Annual Meeting 2020
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April 19, 2023
Chimeric antigen receptor (CAR) T-cell therapy holds much promise in treating B-cell malignancies and multiple myeloma. ...
Low Ejection Fraction Linked to Post-AHCT Survival in Patients with Amyloidosis
Rebecca Araujo
ASH Annual Meeting 2020
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July 5, 2023
Findings presented at the 2020 American Society of Hematology Annual Meeting & Exposition suggest that ejection ...
Ixazomib Plus Cyclophosphamide and Dexamethasone for Newly Diagnosed AL Amyloidosis
Rebecca Araujo
ASH Annual Meeting 2020
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April 19, 2023
A regimen of ixazomib, cyclophosphamide, and dexamethasone produced hematologic responses in 57% of patients with ...
MRD Status in Bone Marrow, Peripheral Blood May Predict Post-AHCT Survival in Patients with MCL
DocWire News Editors
ASH Annual Meeting 2020
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April 3, 2023
In younger patients with mantle cell lymphoma (MCL), pre-transplant MRD status in both bone marrow and peripheral blood ...
Zanubrutinib Is Well Tolerated, Associated with High Clinical Activity in R/R Waldenstrom Macroglobulinemia
DocWire News Editors
ASH Annual Meeting 2020
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April 6, 2023
Treatment with zanubrutinib was well tolerated and associated with high clinical activity in patients with ...
Novel DNA Vaccine Reduces Tumor Clones, Favorably Alters Immune Microenvironment in Patients with Untreated Smoldering WM
DocWire News Editors
ASH Annual Meeting 2020
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August 31, 2023
A novel idiotype (scFv-CCL20) DNA vaccine was associated with favorable perturbation of the immune microenvironment in ...
Adding Rituximab to Ixazomib as Post-AHCT Maintenance in MCL Increases Risk of Myelosuppression
DocWire News Editors
ASH Annual Meeting 2020
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August 28, 2023
A study has found that the addition of rituximab to ixazomib, when used as maintenance therapy following autologous ...
First-Line Ibrutinib Plus Venetoclax Improves Rates of uMRD in Patients With CLL and SLL
DocWire News Editors
ASH Annual Meeting 2020
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August 28, 2023
A first-line regimen consisting of once-daily ibrutinib plus venetoclax was associated with high rates of undetectable ...
Early Initiation of Zanubrutinib in CLL Improves Response, Durable Survival
DocWire News Editors
ASH Annual Meeting 2020
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April 6, 2023
Early initiation of Bruton’s tyrosine kinase inhibitor zanubrutinib in patients with chronic lymphocytic leukemia ...
Patients with AL Amyloidosis at Higher Risk for Severe COVID-19
Rebecca Araujo
ASH Annual Meeting 2020
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April 19, 2023
Individuals with light-chain (AL) amyloidosis have higher odds of severe SARS-CoV-2 infection or mortality compared with ...
Isatuximab Is Safe and Effective for Previously Treated AL Amyloidosis
Rebecca Araujo
ASH Annual Meeting 2020
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April 19, 2023
Therapy with isatuximab for previously treated light-chain (AL) amyloidosis was found to be effective and safe, ...
Study Explores Direct Medical Costs After Patients With High-Risk MDS Discontinue Hypomethylating Agents
DocWire News Editors
ASH Annual Meeting 2020
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August 30, 2023
Hypomethylating agents (HMAs) are the current standard of care in patients with high-risk myelodysplastic ...
Survey Asks European Physicians About Blood Supply Shortages and Factors That Affect Outcomes in Patients With MDS
DocWire News Editors
ASH Annual Meeting 2020
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August 30, 2023
Many patients with myelodysplastic syndromes (MDS) are dependent on blood transfusions. Therefore, sufficient blood ...
Financial Intervention Decreases Mortality in Patients With Hematologic Malignancy
DocWire News Editors
ASH Annual Meeting 2020
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August 30, 2023
Patients with cancer often face financial toxicity due to the effects of disease on the ability to work, as well as the ...
Study Defines Cutoff to Stratify Patients with Intermediate Risk According to IPSS-R
DocWire News Editors
ASH Annual Meeting 2020
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August 24, 2023
The Revised International Prognostic Scoring System (IPSS-R) is a useful tool to predict clinical outcomes in patients ...
Hem/Onc Roundup: Highlights from ASH 2020, Disparities in Cancer Surgery Survival, and more
Rebecca Araujo
ASH Annual Meeting 2020
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April 19, 2023
Postoperative Cancer Mortality Is Declining, But Racial Disparities Are Not Changing ...
ASH 2020: Dr. Wierda Discusses Phase 2 CAPTIVATE Study Data
Kaitlyn D’Onofrio
ASH Annual Meeting 2020
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April 10, 2023
William Wierda, MD, Professor, Department of Leukemia, The University of Texas MD Anderson Cancer Center, presented data ...
Single-Agent Loncastuximab Induces Response in Patients with DLBCL
DocWire News Editors
ASH Annual Meeting 2020
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April 6, 2023
A study presented at the 2020 ASH Annual Meeting found that loncastuximab, a humanized anti-CD19 antibody, had ...
Socioeconomic Disparities Impact Access to Care for Patients with DLBCL
DocWire News Editors
ASH Annual Meeting 2020
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April 6, 2023
Guidelines from the World Health Organization and National Comprehensive Cancer Network recommend that all patients with ...
Effects of a Dual-Targeting CD19/22 CAR T-Cell Therapy in Combination with Pembrolizumab for DLBCL
DocWire News Editors
ASH Annual Meeting 2020
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August 28, 2023
AUTO3 is a chimeric antigen receptor (CAR) T-cell targeting CD19/22 with limited duration of PD-1 blockade. A study ...
Renal Function Does Not Impact Efficacy of Selinexor in Patients with DLBCL
DocWire News Editors
ASH Annual Meeting 2020
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April 6, 2023
A study presented at the 2020 ASH Annual Meeting found that the efficacy of selinexor in patients with ...
Tumor Lysis Syndrome in Venetoclax-Treated CLL in Clinical Trial, Real-World Patients
Kaitlyn D’Onofrio
ASH Annual Meeting 2020
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May 2, 2023
Venetoclax (Ven) has helped patients with chronic lymphocytic leukemia (CLL) achieve improved long-term outcomes with ...
Venetoclax Retreatment May Yield High Response Rate in CLL
Kaitlyn D’Onofrio
ASH Annual Meeting 2020
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May 2, 2023
A fixed-duration venetoclax (Ven)-based regimen is considered a standard of care (SOC) option for patients with ...
Study Discusses Real-World Registry Data on Biomarker Testing, Treatment Patterns in Patients with CLL/SLL
Kaitlyn D’Onofrio
ASH Annual Meeting 2020
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May 2, 2023
The introduction of novel agents has given patients with chronic lymphocytic leukemia (CLL) and small lymphocytic ...
The Effects of PFS, Toxicity Risks on Choosing Novel Agents in CLL
Kaitlyn D’Onofrio
ASH Annual Meeting 2020
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May 2, 2023
The introduction of novel agents has changed the treatment landscape for chronic lymphocytic leukemia (CLL), but these ...
Real-World Data on First-Line Ibrutinib or Chemoimmunotherapy Outcomes in CLL By Risk Status
Kaitlyn D’Onofrio
ASH Annual Meeting 2020
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May 2, 2023
The prognosis for high-risk (HR) chronic lymphocytic leukemia (CLL) is poor. Clinical data have found that small ...
ASH 2020: ZUMA-12 Study Assesses CAR T-Cell Therapy as Frontline Treatment for Large B-Cell Lymphoma
Kerri Fitzgerald
ASH Annual Meeting 2020
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April 10, 2023
Sattva S. Neelapu, MD, of the University of Texas MD Anderson Cancer Center in Houston, TX, discusses outcomes from the ...
ASH 2020: Could the Combo Daratumumab, Pomalidomide, and Dexamethasone Be Used in an Earlier Line of Therapy?
Kerri Fitzgerald
ASH Annual Meeting 2020
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April 10, 2023
Meletios A. Dimopoulos, MD, of the National and Kapodistrian University of Athens in Greece, discusses outcomes from the ...
ASH 2020: GRIFFIN Study Assesses Quadruplet Therapy with Daratumumab, Lenalidomide, Bortezomib, and Dexamethasone for Multiple Myeloma
Kerri Fitzgerald
ASH Annual Meeting 2020
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April 10, 2023
Peter M. Voorhees, MD, of the Levine Cancer Institute, Atrium Health in Charlotte, NC, discusses outcomes from the phase ...
Can an MRD Assay Better Predict DLBCL Disease Progression?
Kerri Fitzgerald
ASH Annual Meeting 2020
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April 6, 2023
Researchers assessed the use of a next-generation sequencing (NGS)-based minimal residual disease (MRD) assay for early ...
Which of These Treatment Combinations Extend Survival for DLBCL?
Kerri Fitzgerald
ASH Annual Meeting 2020
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April 6, 2023
A real-world study presented at the 2020 ASH Annual Meeting observed no significant survival differences in patients ...
Acalabrutinib Plus R-CHOP for Untreated DLBCL
Kerri Fitzgerald
ASH Annual Meeting 2020
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April 3, 2023
Acalabrutinib in combination with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) was ...
Does Race Influence DLBCL Survival?
Kerri Fitzgerald
ASH Annual Meeting 2020
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April 6, 2023
A study presented at the 2020 ASH Annual Meeting assessed whether there was a survival difference between Hispanic (HI) ...
Financial Burden May Lead to Delayed Care in Patients with CLL
DocWire News Editors
ASH Annual Meeting 2020
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May 2, 2023
Patients with cancer may experience financial burden due to medical expenses, job disruption/loss, and other factors. ...
ASH 2020: Raymond Comenzo, MD, Discusses Darzalex Faspro for AL Amyloidosis
Rebecca Araujo
ASH Annual Meeting 2020
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April 28, 2023
...
Study Uses Hemoglobin as a Continuous Variable to Refine Prognosis in Myelodysplastic Syndromes
DocWire News Editors
ASH Annual Meeting 2020
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August 24, 2023
The Revised International Prognostic Scoring System (IPSS-R) is the standard tool to predict prognosis for patients with ...
CVD Significantly Affects Survival in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndromes
DocWire News Editors
ASH Annual Meeting 2020
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August 24, 2023
Research presented at the 62nd ASH Annual Meeting & Exposition indicates that the presence of cardiovascular disease ...
A Tool to Improve the Diagnostic Accuracy of Myelodysplastic Syndromes
DocWire News Editors
ASH Annual Meeting 2020
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August 24, 2023
Histological and cytomorphological examinations are vital to diagnosis of myelodysplastic syndromes (MDS). But accurate ...
National MDS Study: Targeted Sequencing of Seven Genes Can Help Reduce Misclassification
DocWire News Editors
ASH Annual Meeting 2020
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August 24, 2023
According to research presented at the 62nd ASH Annual Meeting & Exposition, combining pathology reviews with ...
Novel Small Molecule Effectively Silences MYD88, Gene Frequently Mutated in Waldenstrom Macroglobulinemia
DocWire News Editors
ASH Annual Meeting 2020
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April 6, 2023
The use of NSC12, a novel small molecule that specifically halts the FGF/FGFR axis in Waldenstrom macroglobulinemia ...
Residual Lymphadenopathy Associated with Partial Response After VenG in CLL
DocWire News Editors
ASH Annual Meeting 2020
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April 6, 2023
Patients with chronic lymphocytic leukemia (CLL) who have mild residual lymphadenopathy are more likely to have a ...
Duvelisib/Venetoclax Shows Promising Clinical Activity in Patients With CLL/SLL and Richter’s Syndrome
DocWire News Editors
ASH Annual Meeting 2020
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April 6, 2023
A combination regimen consisting of duvelisib and venetoclax was well tolerated, clinically active, and led to ...
Older Age, Low Albumin, and High LDH Predict Worse Prognosis in Patients with Waldenstrom Macroglobulinemia
DocWire News Editors
ASH Annual Meeting 2020
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April 6, 2023
A real-world retrospective analysis found old age, low platelet count, low albumin, high β-2 microglobulin, high ...
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